CryoIQ DERM Plus Liquid Freeze Therapy - Device, Cartridge And Case

Professional Precision Cryotherapy Treatment Device

A professional cryotherapy device designed for controlled, targeted freezing of common dermatological lesions, supplied as a complete kit with applicator, gas cartridge, and protective storage case.

Best for: Qualified healthcare and aesthetic professionals seeking a precise, pen-style cryotherapy device for the management of benign skin lesions such as warts, verrucas, corns, and similar conditions.

Not ideal for: Non-professional or unsupervised use, treatment of lesions of uncertain diagnosis, or situations where cryotherapy is contraindicated. Not available to general public.

• Pen-style precision application for controlled treatment areas
• Consistent cooling performance using nitrous oxide technology
• Supplied as a complete, clinic-ready kit

What is it?

The CryoIQ DERM Plus is a professional cryotherapy device developed to support the targeted treatment of a wide range of superficial skin lesions. It uses a nitrous oxide (N₂O) gas cartridge and an advanced internal filtering system to deliver consistent, controlled freezing to the selected area.

Designed to be used like a pen, the device allows clinicians to apply cryotherapy with accuracy, focusing treatment on the lesion itself while helping to minimise exposure to surrounding healthy tissue. This controlled approach is particularly valuable in podiatry, dermatology-adjacent care, and aesthetic practice, where precision and predictability are essential.

The CryoIQ DERM Plus is classified as a Class IIa medical device, reflecting its intended professional use and its compliance with relevant safety and performance standards. 

It is supplied with a cartridge, applicators, and a protective case, allowing it to be integrated into clinical workflows with minimal additional setup.

Who is it for?

This device is intended for trained professionals who are competent in the assessment and treatment of benign skin lesions using cryotherapy techniques. Typical users include podiatrists, foot health practitioners (where permitted), dermatology professionals, and beauty or aesthetic therapists working within their defined scope of practice.

It is particularly suited to practitioners who:

• Require precise lesion targeting rather than broad-area freezing.
• Prefer a pen-style, hand-controlled device for confidence and accuracy.
• Value consistent cooling performance between treatments.
• Need a portable, clinic-friendly solution with a dedicated storage case.
• Want a cost-conscious cryotherapy option with efficient cartridge usage.

What does it help with?

The CryoIQ DERM Plus is designed to support the controlled application of cryotherapy for a variety of benign dermatological indications. It does not replace diagnosis or clinical judgement, but it provides a reliable method of delivering therapeutic freezing where cryotherapy is clinically appropriate.

Condition-to-practical benefit examples

• Warts and verrucas: targeted freezing helps destroy affected tissue while limiting spread to surrounding skin.
• Corns: controlled application can assist in managing localized hyperkeratotic lesions.
• Skin tags: precise applicators help focus treatment on the base of the lesion.
• Actinic and seborrheic keratoses: controlled depth and area of freeze support careful lesion management.
• Angiomas and hemangiomas: selective freezing can be applied where clinically appropriate.
• Molluscum contagiosum: targeted treatment helps address individual lesions.
• Other benign lesions: such as dermatofibromas, sun spots, condylomas, acne-related lesions, and keloids, where cryotherapy is considered suitable by the practitioner.

How does it work?

The CryoIQ DERM Plus uses a pressurised nitrous oxide cartridge to generate extremely low temperatures at the applicator tip. When activated, the device can reach temperatures as low as approximately -80°C, delivering cold energy to a depth of up to around 3 mm, depending on application time and technique.

An internal filter system helps regulate gas flow, supporting a more consistent and prolonged freezing effect compared to simpler aerosol-based systems. The adjustable cold level allows the practitioner to tailor the intensity and duration of freezing to the lesion type, size, and location.

The gold-plated metal applicator supports durability and precise thermal transfer. Interchangeable spray freezing applicators (Ø1–6 mm) and a freeze limiter allow clinicians to further control the treatment area, helping to maintain accuracy and repeatability between sessions.

Expected comfort and use timeline

During treatment: Cryotherapy typically produces a cold or stinging sensation. The pen-style control and adjustable cold level allow practitioners to balance effectiveness with patient comfort. Anaesthesia is generally not required, though individual sensitivity varies.

Immediately after application: The treated area may appear white (frosted) initially, followed by redness or mild swelling as tissue rewarms. These responses are typical of cryotherapy and should be explained to patients as part of informed consent.

Short-term (days): Treated lesions may blister, darken or scab depending on lesion type and treatment depth. Healing timelines vary. Patients should be advised on aftercare and signs that require review.

Ongoing management: Some lesions may require repeat applications. The CryoIQ DERM Plus supports consistent re-treatment where clinically indicated.

Problem and solution overview

Key benefits

• High level of control for targeted cryotherapy applications
• Consistent freezing performance using nitrous oxide technology
• Pen-like handling for confidence and accuracy during treatment
• Durable gold-plated metal applicator
• Supplied as a complete kit for immediate professional use
• Cost-effective cartridge-based system for ongoing treatments

Common mistakes to avoid

• Treating lesions without clear diagnosis: uncertain or suspicious lesions should be referred appropriately.
• Over-freezing: excessive duration or intensity can increase tissue damage and healing time.
• Incorrect applicator choice: using too large a spray diameter may affect healthy skin.
• Poor aftercare advice: patients should be informed about expected reactions and care.

How to use

1. Prepare the device: Insert the N₂O gas cartridge according to the user guide.
2. Select the applicator: Choose the appropriate spray freezing applicator size and fit the freeze limiter if required.
3. Assess the lesion: Confirm indication, size, and suitability for cryotherapy.
4. Apply treatment: Position the pen-style applicator and activate freezing for the clinically appropriate duration.
5. Monitor tissue response: Observe frosting and immediate skin reaction.
6. Provide aftercare guidance: Advise on expected changes and when to seek review.
7. Clean and store: Clean the applicator as instructed and store the device in its case.

Technical specifications

Frequently asked questions

Is the CryoIQ DERM Plus suitable for podiatry use?

Yes. It is commonly used in podiatry settings for conditions such as warts, verrucas, and corns, provided the practitioner is trained and operating within their scope of practice.

Does it require anaesthesia?

In many cases, cryotherapy can be performed without anaesthesia. Sensation varies by patient and lesion location, and clinical judgement should be used.

How precise is the treatment area?

The pen-style design, adjustable spray diameter, and freeze limiter are intended to support accurate targeting of lesions while limiting exposure to surrounding tissue.

Can it be used for multiple lesion types?

Yes. The adjustable cold level and applicator options make it suitable for a wide range of benign dermatological indications when cryotherapy is appropriate.

How long does a cartridge last?

Cartridge usage depends on treatment duration and frequency. The internal filter system is designed to support efficient, consistent gas use.

Is maintenance required?

Routine cleaning of the applicator and correct storage in the supplied case are recommended to maintain performance and longevity.

Can it be used in aesthetic practice?

It is used by beauty and aesthetic professionals where permitted, provided treatments remain within appropriate training and regulatory frameworks.

Can I purchase an additional tip?

Additional parts available - Cryoalfa-S Applicator - Diam 1-6mm - Glass Tip for Spray Freezing 60µ - Call to Order code NV3643

Complementary product suggestions

This device can be complemented with appropriate aftercare products, protective dressings, and clinical consumables used in cryotherapy workflows. In podiatry or dermatology-adjacent settings, magnification tools, sterile swabs, and patient information materials may also support safe and effective treatment delivery.

Content credibility

Written by: Algeos Product & Clinical Content Team
Last reviewed: January 2026
Purpose: This content is provided to support informed purchasing decisions and professional product use. It does not replace clinical training, diagnosis, or professional judgement.